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Cladribine Tablets and COVID-19

• EMD Serono is continuing to conduct safety surveillance to identify and evaluate drug safety risks

• As of 15 January 2021, 273 suspected cases of COVID-19 occurring in patients treated with Cladribine Tablets have been reported to the Merck KGaA, Darmstadt, Germany safety database

• Of these 273 cases, 161 cases are positively confirmed COVID-19

image-1

'Medically significant’ specified by the case reporter
aIncludes 11 patients with compatible COVID-19 symptoms but not evaluated further given negative PCR test (3 cases considered serious);
bIncludes 18 patients who were asymptomatic (2 cases considered serious);
cIncludes 9 cases with compatible COVID-19 symptoms and pending outcome (1 case considered serious);
dfollow-up ongoing

Favorable outcomes after COVID-19 infection in multiple sclerosis patients treated with Cladribine Tablets

Jack D, Nolting A, Galazka A

Mult Scler Relat Disord 2020;102469

https://doi.org/10.1016/j.msard.2020.102469

DJ and AN are employees of Merck KGaA, Darmstadt, Germany. AG is an employee of Merck, Aubonne, Switzerland, a division of Merck KGaA, Darmstadt, Germany.

 

• Letter to the editor reporting outcomes of patients receiving Cladribine Tablets who have contracted COVID-19 and have been reported to the Merck KGaA, Darmstadt, Germany Global Patient Safety Database (data cut-off 29 June 2020)