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Cladribine Tablets and COVID-19

• EMD Serono is continuing to conduct safety surveillance to identify and evaluate drug safety risks

• As of 14 May 2021, 455 confirmed or suspected cases of COVID-19 occurring in patients treated with Cladribine Tablets have been reported to the Merck KGaA, Darmstadt, Germany safety database

•Of these 455 cases, 275 cases are positively confirmed COVID-19


Please direct any queries relating to Cladribine Tablets and COVID-19 to the US medical information team.

‘Medically significant’ specified by the case reporter. ‘Not recovered’ and ‘Not resolved’ are the current outcomes at the time of report (14 May 2021). For simplicity of presentation, the outcome ‘Not reported’ also includes those with missing or pending outcomes. aIncludes 6 patients with compatible COVID-19 symptoms but not evaluated further given negative PCR tests. 

Favorable outcomes after COVID-19 infection in multiple sclerosis patients treated with Cladribine Tablets

Jack D, Nolting A, Galazka A

Mult Scler Relat Disord 2020;102469


DJ and AN are employees of Merck KGaA, Darmstadt, Germany. AG is an employee of Merck, Aubonne, Switzerland, a division of Merck KGaA, Darmstadt, Germany.


• Letter to the editor reporting outcomes of patients receiving Cladribine Tablets who have contracted COVID-19 and have been reported to the Merck KGaA, Darmstadt, Germany Global Patient Safety Database (data cut-off 29 June 2020)